Clinical outcomes of Torque teno virus-infected thalassemic patients with and without hepatitis C virus infection

Clinical outcomes of Torque teno virus-infected thalassemic patients with and without hepatitis C virus infection

BACKGROUND Although a marked proportion of thalassemic patients acquire Torque teno virus (TTV) through blood transfusion, its clinical importance is unclear. This study was designed to investigate the clinical importance of TTV infection in thalassemic patients with and without hepatitis C virus (HCV) co-infection in Iran. METHODS In this case-control study, 107 thalassemic patients on chron...

Prevalence of Torque Teno Virus in Healthy Individuals and Peoples Infected with Hepatitis C Virus Living in Yazd, Iran

Phylogenetic Analysis of Torque Teno Virus in Hepatitis C Virus Infected Patients in Shiraz

BACKGROUND Torque teno virus (TTV) was the first human Circoviridae detected in a Japanese patient with unknown hepatitis in 1997. Subsequently, several studies performed to evaluate different aspects of Torque teno virus pathogenesis. OBJECTIVES The present study aimed to determine dominant genotype of Torque teno virus in chronic hepatitis disease using 5΄-UTR sequence among patients infect...

Torque Teno Virus and Hepatitis C Virus Co-Infection in Iranian Pediatric Thalassemia Patients

OBJECTIVE Torque teno virus (TTV) infects patients at risk for parenteral exposure and chronic blood transfusion, such as those with β-thalassemic. This study aimed to assess the prevalence of TTV infection and co-infection of TTV and hepatitis C virus (HCV) in pediatric thalassemia patients receiving chronic blood transfusion. MATERIAL AND METHODS The study included 90 pediatric thalassemia ...

The Absence of Hepatitis C Virus Infection Among Patients with Hepatitis B virus in Mashhad, Iran

Background and Aims: Many studies have provided evidence for the role of hepatitis B and C viruses in the development of liver cancer. Although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with HBV and HCV. This study was performed to determine the frequency of HBV/HCV-coinfection in Mashhad, North-East of Iran. Mat...